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Facts About Prostate Cancer

Prostate cancer is the most prevalent cancer among men in the United States. According to the American Cancer Society, approximately one in six men will be diagnosed with prostate cancer during their lifetime, with about 191,930 new cases expected this year. Fortunately, prostate cancer is often manageable and curable, with over 98% of men surviving more than ten years post-diagnosis.

Treatment Options for Prostate Cancer

Upon diagnosis, it’s essential to discuss treatment options with a multidisciplinary team, including:

  • Radiation Oncologist: A specialist in treating cancer using radiation therapy.
  • Urologist: A surgeon focusing on the urinary and male reproductive systems.
  • Medical Oncologist: A physician specializing in cancer treatment through chemotherapy and targeted therapies.

Treatment modalities for prostate cancer encompass:

  • External Beam Radiation Therapy (EBRT): High-energy radiation is directed at the prostate to eradicate cancer cells.
  • Brachytherapy: Radioactive seeds are implanted directly into the prostate to deliver localized radiation.

In certain cases, combining treatments—such as hormonal therapy with EBRT or brachytherapy with EBRT—may be recommended. It’s crucial to discuss the risks and benefits of all treatment options, including active surveillance, with your healthcare team.

External Beam Radiation Therapy (EBRT)

EBRT involves a series of daily sessions where radiation is precisely targeted to the prostate. This approach can be as effective as, and sometimes more favorable than, surgery for treating prostate cancer.

Prior to initiating treatment, your radiation oncologist will develop a personalized plan based on biopsy results, imaging studies, and physical examinations. A planning CT scan, often referred to as a simulation, is performed to map the treatment area. To enhance accuracy, supportive devices may be used to maintain consistent positioning during treatment. Patients might be instructed to have a full bladder during sessions, and in some cases, a gel is placed between the prostate and rectum to minimize side effects. Non-radioactive marker seeds may also be implanted in the prostate to aid in precise targeting.

The treatment plan may encompass the prostate, seminal vesicles, and, in certain situations, nearby lymph nodes. Advanced imaging techniques, such as 3D conformal radiation therapy (3D-CRT) and intensity-modulated radiation therapy (IMRT), are utilized to focus radiation on the tumor while sparing surrounding healthy tissues. Image-guided radiation therapy (IGRT) further enhances precision by using imaging before each session to ensure accurate delivery.

Treatment schedules vary:

  • Conventional Fractionation: Typically spans seven to nine weeks.
  • Hypofractionation: Delivers slightly higher doses over four to six weeks, with studies indicating comparable outcomes to conventional schedules.
  • Stereotactic Body Radiation Therapy (SBRT): Administers high doses over one to three weeks, usually in five sessions. While SBRT is under investigation for long-term side effects, it may be suitable for select patients.

Most EBRT treatments employ high-energy X-rays (photons). Proton beam therapy, which uses protons instead of photons, is available at select centers and may be considered for certain patients.

Prostate Brachytherapy

Brachytherapy involves placing radioactive sources directly into the prostate and is categorized into:\

  1. Low-Dose-Rate (LDR) Brachytherapy: Permanent implantation of small radioactive seeds into the prostate. This outpatient procedure requires anesthesia. The seeds emit radiation over several months and remain harmless in the prostate after their radioactivity diminishes. During the initial period, patients should avoid close contact with children and pregnant women. Specific safety guidelines will be provided by your healthcare team.
  2. High-Dose-Rate (HDR) Brachytherapy: Temporary insertion of catheters into the prostate, through which a radioactive source delivers radiation over one to two days. This procedure also requires anesthesia. After treatment, no radioactivity remains in the body, and no special precautions are necessary.

Brachytherapy can be administered alone or in combination with EBRT and hormonal therapy, depending on individual patient factors.

Self-Care During Treatment

To support healing and manage potential side effects during radiation therapy:

  • Adhere to Medical Advice: Follow your healthcare team’s instructions diligently.
  • Communicate Openly: Discuss any concerns or questions with your doctors; no question is trivial.
  • Review Medications: Inform your doctor about all medications, vitamins, or supplements you’re taking to ensure they are safe during treatment.
  • Maintain a Balanced Diet: Proper nutrition supports overall health and recovery.

Completing treatment and recovery can be challenging. Seek out help from support groups and friends ahead of time. If you have a support network in place before and during treatment, it will be easier to get through side effects, since people you can count on will be around to help you. If you need additional support, let your doctor and nurse know.

Potential Side Effects

Side effects vary among individuals and may include:

  • Urinary Symptoms: Increased frequency, urgency, or a weaker stream, sometimes accompanied by mild discomfort. These symptoms are more pronounced with brachytherapy but can be managed with medications.
  • Bowel Changes: Urgency, loose stools, diarrhea, increased gas, or hemorrhoid flare-ups. These effects are typically temporary.
  • Fatigue: Mild tiredness may develop during treatment but usually improves within a few weeks post-therapy.
  • Skin Irritation: Mild irritation may occur with EBRT; gentle cleansing with mild soap and warm water is recommended.
  • Sexual Function: Erectile dysfunction is a potential side effect of prostate cancer treatments. The risk depends on pre-treatment erectile function. Discuss concerns with your doctor, who can suggest remedies or prescribe medications.
  • Fertility: Radiation can impact fertility. If you plan to have children post-treatment, consider sperm banking before therapy.

Managing side effects during prostate cancer treatment is crucial for maintaining your well-being. Medications and dietary adjustments can often alleviate symptoms. It’s important to discuss any discomfort or concerns with your healthcare team, who can provide personalized recommendations to help you feel better.

If you have questions about your diagnosis, treatment options, or potential side effects, please contact our office to schedule a consultation with one of our radiation oncologists.

About Our Radiation Oncology Team

Dr. O’Connor and Dr. Montes are experienced radiation oncologists specializing in cancer treatment using radiation therapy. Our multidisciplinary team includes radiation therapists, physicists, dosimetrists, radiation oncology nurses, medical assistants, an oncology nurse navigator, and certified nutrition specialists. We are committed to providing comprehensive care tailored to your individual needs.

© American Society for Radiation Oncology, 2019.