Head and neck cancers encompass malignancies in areas such as the oral cavity, pharynx, larynx, nasal cavity, and salivary glands. According to the American Cancer Society, approximately 54,010 individuals in the United States are diagnosed with head and neck cancers annually, with an estimated 10,850 fatalities resulting from these diseases.
The management of head and neck cancers is tailored based on factors including the cancer type, tumor size, stage, location, and the patient’s overall health. A multidisciplinary team—comprising a surgeon, radiation oncologist, and medical oncologist—collaborates to develop an optimal treatment plan. For early-stage cancers, surgery or radiation therapy may suffice. Advanced cases often require a combination of surgery, radiation therapy, and chemotherapy to achieve the best outcomes.
Radiation therapy plays a pivotal role in treating head and neck cancers by targeting cancer cells while sparing surrounding healthy tissue. Advancements in radiation technology have enhanced the preservation of critical structures, leading to improved functional outcomes in speech and swallowing compared to surgical interventions. In certain scenarios, radiation therapy is combined with surgery, chemotherapy, or both to enhance treatment efficacy.
This modality delivers high-energy X-rays to the tumor site, typically administered daily from Monday to Friday over five to seven weeks. Occasionally, treatments may be scheduled twice daily, depending on the specific case.
Prior to initiating treatment, a planning session known as simulation is conducted. During this session, imaging studies such as CT scans are performed to delineate the treatment area. To ensure precise positioning during therapy, a custom-fitted mask may be created to minimize head and neck movement. Additionally, small skin markings or mask-based markers are used to guide accurate treatment delivery.
Several advanced techniques are employed in external beam radiation therapy:
Internal radiation therapy is also called brachytherapy. This treatment involves inserting radioactive material into a tumor or surrounding tissue to give a more focused dose of radiation. For head and neck cancers, brachytherapy is often used with external beam radiation therapy. It may also be used alone or after surgery. During brachytherapy, your radiation oncologist places thin, hollow, plastic tubes into the tumor and surrounding tissue. These tubes are loaded with tiny radioactive seeds that remain in place for a short time to kill the cancer. The seeds and the tubes are then removed. With low dose rate brachytherapy, the seeds will be left in place for one to three days. For high dose rate brachytherapy, a single radioactive seed stops at various positions along the tubes for short intervals to deliver the dose. It is usually administered in a few sessions over two or more days.
Oral health is a critical component of preparing for head and neck radiation therapy. A dental evaluation is recommended prior to treatment initiation to address any existing dental issues, as radiation can increase the risk of oral complications. Preventive measures, such as fluoride treatments, may be advised to protect teeth during and after therapy. If dental extractions or other procedures are necessary, they should be completed before starting radiation to allow adequate healing time.
Maintaining overall well-being during radiation therapy is essential. Patients are encouraged to:
Radiation therapy may lead to side effects, which vary among individuals. Common side effects include:
Many of these side effects can be managed with medications and supportive care. It’s important to report any discomfort to the healthcare team promptly to receive appropriate interventions.
Dr. O’Connor and Dr. Montes are experienced radiation oncologists specializing in the treatment of cancer using radiation therapy. Our multidisciplinary team includes radiation therapists, physicists, dosimetrists, oncology nurses, medical assistants, an oncology nurse navigator, and certified nutrition specialists, all dedicated to providing comprehensive and compassionate care throughout your treatment journey.
© American Society for Radiation Oncology, 2019.